Employment
75,198
Total employees (Census CBP)
Manufacturing ·NAICS 325414
NAICS 325414 · IRS SOI 2023 · Census CBP
Biological Product (except Diagnostic) Manufacturing - Industry Benchmarks
$125,302/yr average annual pay, with 8 SBA loans on record for NAICS 325414.
- 441
- Establishments
- 75K
- Workers employed
- $125,302/yr
- Avg payroll / employee
- $2M
- SBA lending, FY20–26
Data updated July 2026
The verdict · NAICS 325414
Pennsylvania leads Biological Product (except Diagnostic) Manufacturing activity nationally, across 441 establishments employing 75K workers. IRS SOI doesn't publish margin data at this NAICS level.
- 441
- Business establishments (Census)
- 75K
- Workers employed (Census CBP)
- $125,302/yr
- Avg payroll / employee
- $2M
- SBA lending, FY20–26
Benchmarking Insights for Biological Product (except Diagnostic) Manufacturing
Biological Product (except Diagnostic) Manufacturing sits inside Manufacturing.
441 establishments employ 75,198 workers (170.5/location) at $125,302/yr average annual pay. Pennsylvania leads employment, followed by Michigan and Massachusetts.
Avg Payroll / Employee
$125,302/yr
Annual compensation
Establishments
441
Business locations
Release-over-release change
What changed from Census CBP 2022 to 2023
Employment increased by 2,853; establishment count increased by 18. This comparison uses two published national Census County Business Patterns releases; suppressed fields are omitted rather than estimated.
Workforce scale
Financial Detail
- Annual Payroll (Total)
- $9.4B
- Avg Employees per Establishment
- 170.5
Top States by Employment
| State | Employment |
|---|---|
| Pennsylvania | 11,182 |
| Michigan | 5,076 |
| Massachusetts | 4,839 |
| Maryland | 2,563 |
| New Jersey | 2,442 |
| Kansas | 2,041 |
| Florida | 1,132 |
| Minnesota | 798 |
| Indiana | 706 |
| Colorado | 109 |
Showing top 10 of 35 states
SBA Lending Activity
SBA FY2020–2026SBA Loans Approved
8
Total Loan Volume
$2M
Avg Loan Size
$304K
Jobs Supported
68
Program Breakdown
7(a) 7 (88%)
504 1 (12%)
Top SBA Lender
Cache Valley Bank
2 loans in this industry
New Business Share
25.0% of borrowers were new/startup businesses
Annual Lending Trend (5 yrs)
2020 2
2021 1
2023 1
2024 2
2025 2
Frequently Asked Questions
How many businesses are in Biological Product (except Diagnostic) Manufacturing?
441 business establishments. Together they employ 75,198 workers.
What is the average payroll per employee in Biological Product (except Diagnostic) Manufacturing?
$125,302/yr average annual pay per employee. Businesses average 170.5 employees per establishment.
Which states have the most Biological Product (except Diagnostic) Manufacturing employment?
Pennsylvania leads with 11,182 workers. Michigan (5,076) and Massachusetts (4,839) round out the top three.
How much SBA lending does Biological Product (except Diagnostic) Manufacturing receive?
Biological Product (except Diagnostic) Manufacturing businesses received 8 SBA loans totaling $2 million between FY2020 and FY2026. The average loan size was $304K. These loans supported 68 jobs at origination. Most lending (88%) came through the SBA 7(a) program.
Comparable industry benchmarks
These links are calculated from the current national dataset. They are comparison paths, not recommendations or evidence that businesses operate alike.
How this ranks: Its Census employment total exceeds 66% of that same 801-industry cohort. Calculated by ranking this industry's reported value against every other industry at the same NAICS digit-level, not the whole dataset: comparing a 6-digit detail industry to a 2-digit sector would mix incompatible scales.
Closest workforce scale
Same NAICS detail level, ordered by the smallest difference in reported Census employment.
Benchmarking Biological Product (except Diagnostic) Manufacturing
- No margin data, check the parent industry. Browse Manufacturing
- 441 establishments, 75,198 workers. Payroll benchmarks
- 8 SBA loans on record. SBA lending rankings
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.
Sources: IRS Statistics of Income (SOI) Business Tax Statistics · Census Bureau County Business Patterns 2023
NAICS 325414 · Data year: 2023
According to the U.S. Census Bureau, which released its 2023 County Business Patterns dataset in June 2025, PlainBizBench benchmarks 2,002 U.S. industries against Internal Revenue Service Statistics of Income data. See our methodology for the full compilation process.
Read our methodology - how this data is sourced, computed, and verified.
Source: U.S. Census Bureau, County Business Patterns / SUSB Industry employment scale, payroll, and firm-size benchmarks · 2023
Every figure on PlainBizBench is rendered directly from federal source data, no number is typed in by an editor. This page aggregates profit-margin, payroll, entity-type, and SBA-lending benchmarks for this industry, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.