Employment
194,991
Total employees (Census CBP)
Professional, Scientific, and Technical Services ·NAICS 541714
NAICS 541714 · IRS SOI 2023 · Census CBP
Research and Development in Biotechnology (except Nanobiotechnology) - Industry Benchmarks
$184,984/yr average annual pay, with 98 SBA loans on record for NAICS 541714.
- 14.0%
- Professional, Scientific, and Technical Services sector margin
- 195K
- Workers employed
- $184,984/yr
- Avg payroll / employee
- $78M
- SBA lending, FY20–26
Data updated July 2026
The verdict · NAICS 541714
California leads Research and Development in Biotechnology (except Nanobiotechnology) activity nationally. IRS SOI doesn't publish margin data at this NAICS level, but the broader Professional, Scientific, and Technical Services sector runs a 14.0% net margin.
- 14.0%
- Professional, Scientific, and Technical Services sector margin (IRS SOI)
- 195K
- Workers employed (Census CBP)
- $184,984/yr
- Avg payroll / employee
- $78M
- SBA lending, FY20–26
Benchmarking Insights for Research and Development in Biotechnology (except Nanobiotechnology)
Research and Development in Biotechnology (except Nanobiotechnology) sits inside Professional, Scientific, and Technical Services, a sector that runs a 14.0% net margin overall.
5,670 establishments employ 194,991 workers (34.4/location) at $184,984/yr average annual pay. California leads employment, followed by Massachusetts and New Jersey.
Avg Payroll / Employee
$184,984/yr
Annual compensation
Establishments
5,670
Business locations
Release-over-release change
What changed from Census CBP 2022 to 2023
Employment increased by 41,220; establishment count increased by 341. This comparison uses two published national Census County Business Patterns releases; suppressed fields are omitted rather than estimated.
Workforce scale
Financial Detail
- Annual Payroll (Total)
- $36.1B
- Avg Employees per Establishment
- 34.4
Top States by Employment
| State | Employment |
|---|---|
| California | 65,114 |
| Massachusetts | 35,946 |
| New Jersey | 10,031 |
| Pennsylvania | 7,937 |
| Maryland | 7,304 |
| Washington | 6,223 |
| Texas | 4,041 |
| Virginia | 2,741 |
| Wisconsin | 1,911 |
| Illinois | 1,833 |
Showing top 10 of 51 states
SBA Lending Activity
SBA FY2020–2026SBA Loans Approved
98
Total Loan Volume
$78M
Avg Loan Size
$794K
Jobs Supported
844
Program Breakdown
7(a) 78 (80%)
504 20 (20%)
Top SBA Lender
Newtek Bank, National Association
8 loans in this industry
New Business Share
24.5% of borrowers were new/startup businesses
Annual Lending Trend (7 yrs)
2020 12
2021 13
2022 12
2023 12
2024 24
2025 23
2026 2
Frequently Asked Questions
How profitable is Research and Development in Biotechnology (except Nanobiotechnology)?
IRS SOI doesn't publish margin data at the NAICS 541714 level. California leads this industry nationally. The broader Professional, Scientific, and Technical Services sector runs a 14.0% net margin (IRS SOI 2023).
How many businesses are in Research and Development in Biotechnology (except Nanobiotechnology)?
5,670 business establishments. Together they employ 194,991 workers.
What is the average payroll per employee in Research and Development in Biotechnology (except Nanobiotechnology)?
$184,984/yr average annual pay per employee. Businesses average 34.4 employees per establishment.
Which states have the most Research and Development in Biotechnology (except Nanobiotechnology) employment?
California leads with 65,114 workers. Massachusetts (35,946) and New Jersey (10,031) round out the top three.
How much SBA lending does Research and Development in Biotechnology (except Nanobiotechnology) receive?
Research and Development in Biotechnology (except Nanobiotechnology) businesses received 98 SBA loans totaling $78 million between FY2020 and FY2026. The average loan size was $794K. These loans supported 844 jobs at origination. Most lending (80%) came through the SBA 7(a) program.
Comparable industry benchmarks
These links are calculated from the current national dataset. They are comparison paths, not recommendations or evidence that businesses operate alike.
How this ranks: Its Census employment total exceeds 85% of that same 801-industry cohort. Calculated by ranking this industry's reported value against every other industry at the same NAICS digit-level, not the whole dataset: comparing a 6-digit detail industry to a 2-digit sector would mix incompatible scales.
Closest workforce scale
Same NAICS detail level, ordered by the smallest difference in reported Census employment.
Benchmarking Research and Development in Biotechnology (except Nanobiotechnology)
- No margin data, check the parent industry. Browse Professional, Scientific, and Technical Services
- 5,670 establishments, 194,991 workers. Payroll benchmarks
- 98 SBA loans on record. SBA lending rankings
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.
Sources: IRS Statistics of Income (SOI) Business Tax Statistics · Census Bureau County Business Patterns 2023
NAICS 541714 · Data year: 2023
According to the U.S. Census Bureau, which released its 2023 County Business Patterns dataset in June 2025, PlainBizBench benchmarks 2,002 U.S. industries against Internal Revenue Service Statistics of Income data. See our methodology for the full compilation process.
Read our methodology - how this data is sourced, computed, and verified.
Source: U.S. Census Bureau, County Business Patterns / SUSB Industry employment scale, payroll, and firm-size benchmarks · 2023
Every figure on PlainBizBench is rendered directly from federal source data, no number is typed in by an editor. This page aggregates profit-margin, payroll, entity-type, and SBA-lending benchmarks for this industry, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.