Employment
45,459
Total employees (Census CBP)
Manufacturing ·NAICS 325413
NAICS 325413 · IRS SOI (C corp) · Census CBP 2023
In-Vitro Diagnostic Substance Manufacturing - Industry Benchmarks
$115,404/yr average annual pay, with 5 SBA loans on record for NAICS 325413.
- 267
- Establishments
- 45K
- Workers employed
- $115,404/yr
- Avg payroll / employee
- $4M
- SBA lending, FY20–26
Data updated August 2026
The verdict · NAICS 325413
California leads In-Vitro Diagnostic Substance Manufacturing activity nationally, across 267 establishments employing 45K workers. IRS SOI doesn't publish margin data at this NAICS level.
- 267
- Business establishments (Census)
- 45K
- Workers employed (Census CBP)
- $115,404/yr
- Avg payroll / employee
- $4M
- SBA lending, FY20–26
Use In-Vitro Diagnostic Substance Manufacturing's NAICS benchmark as a comparison point, not a forecast for one business.
In-Vitro Diagnostic Substance Manufacturing is reported here with financial measures from IRS Statistics of Income and workforce measures from Census County Business Patterns. The page keeps those source systems distinct, shows unavailable fields rather than estimating them, and links the underlying industry context so readers can compare the same NAICS activity before interpreting a margin or payroll figure.
Source: IRS SOI (C corporation headline) and Census County Business Patterns 2023
Benchmarking Insights for In-Vitro Diagnostic Substance Manufacturing
In-Vitro Diagnostic Substance Manufacturing sits inside Manufacturing.
267 establishments employ 45,459 workers (170.3/location) at $115,404/yr average annual pay. California leads employment, followed by New Jersey and New York.
Avg Payroll / Employee
$115,404/yr
Annual compensation
Establishments
267
Business locations
Release-over-release change
What changed from Census CBP 2022 to 2023
establishment count increased by 6. This comparison uses two published national Census County Business Patterns releases; suppressed fields are omitted rather than estimated.
Subscribe to this industry's release updates (RSS)Workforce scale
Financial Detail
- Annual Payroll (Total)
- $5.2B
- Avg Employees per Establishment
- 170.3
Top States by Employment
| State | Employment |
|---|---|
| California | 7,508 |
| New Jersey | 4,440 |
| New York | 3,362 |
| Minnesota | 2,224 |
| Florida | 293 |
Showing top 10 of 27 states
SBA Lending Activity
SBA FY2020–2026SBA Loans Approved
5
Total Loan Volume
$4M
Avg Loan Size
$839K
Jobs Supported
38
Program Breakdown
7(a) 4 (80%)
504 1 (20%)
Top SBA Lender
KeyBank National Association
2 loans in this industry
New Business Share
20.0% of borrowers were new/startup businesses
Annual Lending Trend (3 yrs)
2021 2
2024 1
2025 2
Frequently Asked Questions
How many businesses are in In-Vitro Diagnostic Substance Manufacturing?
267 business establishments. Together they employ 45,459 workers.
What is the average payroll per employee in In-Vitro Diagnostic Substance Manufacturing?
$115,404/yr average annual pay per employee. Businesses average 170.3 employees per establishment.
Which states have the most In-Vitro Diagnostic Substance Manufacturing employment?
California leads with 7,508 workers. New Jersey (4,440) and New York (3,362) round out the top three.
How much SBA lending does In-Vitro Diagnostic Substance Manufacturing receive?
In-Vitro Diagnostic Substance Manufacturing businesses received 5 SBA loans totaling $4 million between FY2020 and FY2026. The average loan size was $839K. These loans supported 38 jobs at origination. Most lending (80%) came through the SBA 7(a) program.
Comparable industry benchmarks
These links are calculated from the current national dataset. They are comparison paths, not recommendations or evidence that businesses operate alike.
According to Census County Business Patterns 2023, In-Vitro Diagnostic Substance Manufacturing ranks #376 of 801 U.S. industries at the 6-digit NAICS level by total employment.
Closest workforce scale
Same NAICS detail level, ordered by the smallest difference in reported Census employment.
Benchmarking In-Vitro Diagnostic Substance Manufacturing
- No margin data, check the parent industry. Browse Manufacturing
- 267 establishments, 45,459 workers. Payroll benchmarks
- 5 SBA loans on record. SBA lending rankings
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.
Sources: IRS Statistics of Income (SOI) Business Tax Statistics · Census Bureau County Business Patterns 2023
NAICS 325413 · CBP 2023 · IRS SOI
According to the U.S. Census Bureau, which released its 2023 County Business Patterns dataset in June 2025, PlainBizBench benchmarks 2,002 U.S. industries against Internal Revenue Service Statistics of Income data. See our methodology for the full compilation process.
Read our methodology - how this data is sourced, computed, and verified.
Source: U.S. Census Bureau, County Business Patterns / SUSB Industry employment scale, payroll, and firm-size benchmarks · 2023
Every figure on PlainBizBench is rendered directly from federal source data, no number is typed in by an editor. This page aggregates profit-margin, payroll, entity-type, and SBA-lending benchmarks for this industry, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.
Disclaimer: Public IRS/Census data, not financial or tax advice. See our full disclaimer.